CD63 Polyclonal Antibody, 100ul[BT-AP02317] Monoclonal Antibodies Mutations in this gene have

Mutations in this gene have been found in patients with Saethre-Chotzen syndrome

which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al

This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway

This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle

It acts as a decoy receptor that competes with death receptors for ligand binding

CD63 Polyclonal Antibody, 100ul[BT-AP02317] Monoclonal Antibodies Mutations in this gene haveCUL3 encodes a member of the cullin protein family. Cullin 3 plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants