Rat Neurogenic Locus Notch Homolog Protein 1, NOTCH1 ELISA Kit, 96T Bio-Reaction Tube especially for normal development of

especially for normal development of the craniofacial skeleton and for normal development of the palate

It plays a role in malignant glioma progression

The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix

The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras

and are functionally distinct

Rat Neurogenic Locus Notch Homolog Protein 1, NOTCH1 ELISA Kit, 96T Bio-Reaction Tube especially for normal development ofFunctions as a receptor for membrane bound ligands Jagged 1 (JAG1), Jagged 2 (JAG2) and Delta 1 (DLL1) to regulate cell fate determination (By similarity). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ RBPSUH and activates genes of the enhancer of split locus (By similarity). Affects the implementation of differentiation, proliferation and apoptotic programs (By