CD43 Rabbit Polyclonal Antibody, 20ul Peptide Synthesis The gamma subunit of the

The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes

Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene

The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules

The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex

and to the subfamily of aminophospholipid-transporting ATPases

CD43 Rabbit Polyclonal Antibody, 20ul Peptide Synthesis The gamma subunit of theThe protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes T lymphocytes monocytes granulocytes and some B lymphocytes. It may be part of a physiologic ligand receptor complex involved in T cell activation. During T cell activation this protein is actively removed from the T cell APC (antigen presenting cell) contact site suggesting a negative regulatory role in adaptive immune response.