FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling ＆Storage Activity of this protein can

Activity of this protein can influence cell adhesion and migration

The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases

Several alternatively spliced transcripts have been described

which may be important for the cellular response to DNA damage

Cleavage of the precursor generates alpha and beta subunits

FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling ＆Storage Activity of this protein canThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal