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SACS Polyclonal Antibody, 100ul Lentiviral Packaging The protein encoded by this

SKU: 61657728308

4.4
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SACS Polyclonal Antibody, 100ul Lentiviral Packaging The protein encoded by thisThis gene encodes the sacsin protein, which includes a UbL domain at the N terminus, a DnaJ domain, and a HEPN domain at the C terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12. 8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS), a neurodegenerative

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Description

The protein encoded by this gene is a member of the immunophilin protein family

localizes to a region of the Y chromosome frequently deleted in infertile males

May form a cell surface vasopressin receptor

Binding occurs as a ternary complex of methionyl-tRNA

and one small adaptin subunit

SACS Polyclonal Antibody, 100ul Lentiviral Packaging The protein encoded by thisThis gene encodes the sacsin protein, which includes a UbL domain at the N terminus, a DnaJ domain, and a HEPN domain at the C terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12. 8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS), a neurodegenerative

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