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SETBP Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Eukaryotic gene transcription is regulated

SKU: 61756897043

4.7
SEK123.75 SEK157.75

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SETBP Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Eukaryotic gene transcription is regulatedThis gene encodes a protein which contains a several motifs including a ski homology region and a SET binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements

An important paralog of this gene is KAT2A

some of which use non-AUG (CUG) translation initiation codon

DVL2 and/or DVL3)

and regulates myogenic and neuronal differentiation

SETBP Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Eukaryotic gene transcription is regulatedThis gene encodes a protein which contains a several motifs including a ski homology region and a SET binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

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