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NMBR Polyclonal Antibody, 50ul[BT-AP06070] Drug Development and Evaluation This protein| along with TAB1

SKU: 61886500776

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NMBR Polyclonal Antibody, 50ul[BT-AP06070] Drug Development and Evaluation This protein| along with TAB1NMBR encodes a 7 transmembrane G protein coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in NMBR may be associated with a

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Description

This protein| along with TAB1 and MAP3K7| also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK)| which may regulate the development and function of osteoclasts

Galanin is an important neuromodulator present in the brain

The mouse gene is located in double minute (DM) chromatin particles

7-transmembrane receptor

and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder

NMBR Polyclonal Antibody, 50ul[BT-AP06070] Drug Development and Evaluation This protein| along with TAB1NMBR encodes a 7 transmembrane G protein coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in NMBR may be associated with a

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