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Rb(Phospho Ser612) Polyclonal Antibody, 50ul sgRNA customized design mediator complex subunit 12 (MED12)

SKU: 61929937842

4.6
USD142.00 USD187.00

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Rb(Phospho Ser612) Polyclonal Antibody, 50ul sgRNA customized design mediator complex subunit 12 (MED12)The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

mediator complex subunit 12 (MED12)

1 μm pore size and a 75 mm diameter PES membrane

Activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions

It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B

including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars

Rb(Phospho Ser612) Polyclonal Antibody, 50ul sgRNA customized design mediator complex subunit 12 (MED12)The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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