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MRP Polyclonal Antibody, 50ul Peptide Library This kinase specifically activates MAPK8/JNK1

SKU: 6196275606

4.6
PLN162.00 PLN196.00

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MRP Polyclonal Antibody, 50ul Peptide Library This kinase specifically activates MAPK8/JNK1This gene encodes a member of the myristoylated alanine rich C kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.

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Description

This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2| and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1| MAP3K2/MEKK2|MAP3K3/MEKK5| and MAP4K2/GCK

The GTP-binding protein Rit1 is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress

Cells with reduced levels of ACAP1 or AKT1 and AKT2 show inhibition of stimulation-dependent cell migration

The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system

MRP Polyclonal Antibody, 50ul Peptide Library This kinase specifically activates MAPK8/JNK1This gene encodes a member of the myristoylated alanine rich C kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.

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