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IκB-alpha Polyclonal Antibody, 100ul[BT-AP10544] Enzyme-Linked Immunosorbent Assay (ELISA) and function of mRNA
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IκB-alpha Polyclonal Antibody, 100ul[BT-AP10544] Enzyme-Linked Immunosorbent Assay (ELISA) and function of mRNAThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell
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