HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos APP encodes a cell surface

APP encodes a cell surface receptor and transmembrane precursor protein (amyloid beta precursor protein) that is cleaved by secretases to form a number of peptides

This gene is intronless and the encoded protein is secreted

Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20

improving the stability of the structure

and a C-terminal hydrophobic region

HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos APP encodes a cell surfaceThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different