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p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 50ul Isothermal Amplification May be involved in actively

SKU: 62380753660

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p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 50ul Isothermal Amplification May be involved in activelyMay be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin dependent kinase activity preventing phosphorylation of critical cyclin dependent kinase substrates and blocking cell cycle progression. induction: By p53 mezerein (antileukemic compound) and interferon beta. PTM: Phosphorylation of Thr 145 by Akt or of Ser 146 by PKC impairs binding to

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Description

May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane

|PTM:Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression

EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation

Alternative splicing results in multiple transcript variants encoding differing isoforms

protein folding and degradation and morphological evolution

p21 (Acetyl Lys154) Rabbit Polyclonal Antibody, 50ul Isothermal Amplification May be involved in activelyMay be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin dependent kinase activity preventing phosphorylation of critical cyclin dependent kinase substrates and blocking cell cycle progression. induction: By p53 mezerein (antileukemic compound) and interferon beta. PTM: Phosphorylation of Thr 145 by Akt or of Ser 146 by PKC impairs binding to

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