SPIT2 Polyclonal Antibody, 20ul Low retention tips The protein encoded by ATM

The protein encoded by ATM belongs to the PI3/PI4-kinase family

and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism

This gene encodes a member of the acyl-Coenzyme A binding protein family| known to function in the transport and distribution of long chain acyl-Coenzyme A in cells

tissue specificity:Seems to be expressed in prostate and less abundantly in adult brain

Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies

SPIT2 Polyclonal Antibody, 20ul Low retention tips The protein encoded by ATMThis gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.