Cdc37(Phospho Ser13) Polyclonal Antibody, 100ul Polyclonal Antibody Preparation Alternatively spliced transcript variants have

Alternatively spliced transcript variants have been described for this gene

as well as in T cell-dependent B cell proliferation and differentiation

Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM)

induction of neuronal cell differentiation

with the second SH3 domain of the adapter protein NCK1

Cdc37(Phospho Ser13) Polyclonal Antibody, 100ul Polyclonal Antibody Preparation Alternatively spliced transcript variants haveThe protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF 1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.