Raf-1 Polyclonal Antibody, 50ul[BT-AP13535] In vitro Assessment F-box proteins interact with SKP1

F-box proteins interact with SKP1 through the F box| and they interact with ubiquitination targets through other protein interaction domains (Jin et al

The importance of the iron binding function has not yet been identified

The encoded protein (distal-less homeobox 5) may play a role in bone development and fracture healing

EDNRA encodes the receptor for endothelin-1

Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed

Raf-1 Polyclonal Antibody, 50ul[BT-AP13535] In vitro Assessment F-box proteins interact with SKP1This gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.