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PP4R1 Polyclonal Antibody, 100ul Cryopreservation The protein encoded by this

SKU: 63904531194

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PP4R1 Polyclonal Antibody, 100ul Cryopreservation The protein encoded by thisThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

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Description

The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A

lung and lymph node

The central core of each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK)

Diseases associated with SERPINB5 include mandibular cancer and laryngeal carcinoma

consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55

PP4R1 Polyclonal Antibody, 100ul Cryopreservation The protein encoded by thisThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

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