APC Polyclonal Antibody, 50ul[BT-AP00507] Cell Dissociation Studies of the orthologous gene

Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion

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The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant

This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation

APC Polyclonal Antibody, 50ul[BT-AP00507] Cell Dissociation Studies of the orthologous geneAPC encodes a tumor suppressor protein (APC, WNT signaling pathway regulator) that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in APC cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a