HLA Class I Polyclonal Antibody, 50ul[BT-AP10062] Bottle-Top Dispenser In adults| higher level expression

In adults| higher level expression is seen in the placenta| lung| kidney| and pancreas than in the heart| brain| liver and skeletal muscle

the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains

this protein is cleaved in a caspase-dependent way

5% of the human genome and encodes over 1

Among its related pathways are Packaging Of Telomere Ends

HLA Class I Polyclonal Antibody, 50ul[BT-AP10062] Bottle-Top Dispenser In adults| higher level expressionHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon