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AR Polyclonal Antibody, 100ul[BT-AP14285] Low-speed Centrifuges Alternatively spliced variants have also

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AR Polyclonal Antibody, 100ul[BT-AP14285] Low-speed Centrifuges Alternatively spliced variants have alsoThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This

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Description

Alternatively spliced variants have also been described for this gene

Binding and activation of the receptor stimulates Janus protein kinases| which in turn phosphorylate several proteins| including STAT1 and STAT2

and transport between the recycling endosome and the trans-Golgi network

is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR

The encoded protein is localized in the inner membrane and facilitates the rapid transport and exchange of molecules between the cytosol and the mitochondrial matrix space

AR Polyclonal Antibody, 100ul[BT-AP14285] Low-speed Centrifuges Alternatively spliced variants have alsoThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This

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