HMG-17(Phospho Ser29) Polyclonal Antibody, 20ul Lentiviral Packaging Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene

The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance

followed by amplification of the retroposed gene

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene

Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed: 15314155

HMG-17(Phospho Ser29) Polyclonal Antibody, 20ul Lentiviral Packaging Multiple alternatively spliced transcript variantsThe protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi.