FEV Polyclonal Antibody, 100ul 3D Culture Multiple transcript variants encoding different

Multiple transcript variants encoding different isoforms have been found for PLA2G4C

This gene is a candidate gene for Hirschsprung disease

Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses

Mutations in this gene are associated with mental retardation

The encoded protein is suggested to play a role in the ER-Golgi protein trafficking

FEV Polyclonal Antibody, 100ul 3D Culture Multiple transcript variants encoding differentFEV (FEV, ETS transcription factor) belongs to the ETS transcription factor family. ETS family members have a highly conserved 85 amino acid ETS domain that binds purine rich DNA sequences. The alanine rich C terminus of this gene indicates that it may act as a transcription repressor. FEV is exclusively expressed in neurons of the central serotonin (5 HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression,