OX2R Polyclonal Antibody, 20ul Proteases Reduced expression of this gene

Reduced expression of this gene in mouse fibroblasts causes short cilia and failure of ciliogenesis

Mutations in this gene have been associated with thrombophilia due to protein C deficiency| neonatal purpura fulminans| and recurrent venous thrombosis

A pseudogene of this gene is located on chromosome 22

Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine

May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa

OX2R Polyclonal Antibody, 20ul Proteases Reduced expression of this geneThe protein encoded by this gene is a G protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G protein coupled receptor that selectively binds orexin A.