CLCN5 Polyclonal Antibody, 50ul Sealing Film The encoded protein (complement C6)

The encoded protein (complement C6) is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis

and thus play a role in cell migration

an event that can trigger a protein-protein interaction cascade which may ultimately effect gene expression and cellular function

belongs to the BAGE family

The extracellular domains interact in a homophilic manner to specify differential cell-cell connections

CLCN5 Polyclonal Antibody, 50ul Sealing Film The encoded protein (complement C6)This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.