CENPS Polyclonal Antibody, 50ul Centrifuges The protein (BLK proto-oncogene

The protein (BLK proto-oncogene

The protein is expressed in the photoreceptor layer of the retina| and the gene is mutated in autosomal recessive retinitis pigmentosa

The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line

The new amino terminus functions as a tethered ligand and activates the receptor

This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue

CENPS Polyclonal Antibody, 50ul Centrifuges The protein (BLK proto-oncogeneThis gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID 31 domain, similar to that found in TATA box binding protein associated factor, TAF(II)31, which is required for p53 mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death