DNJB2 Polyclonal Antibody, 100ul Sealing Film this gene could potently suppress

this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity

Variation in this gene has been associated with cerebellar ataxia

secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling

Alternatively spliced transcript variants encoding multiple isoforms have been observed for SPHK2

Other variants exist

DNJB2 Polyclonal Antibody, 100ul Sealing Film this gene could potently suppressThis gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.