Human Hypoxia-inducible Factor 1Α, HIF-1A ELISA Kit , 96T Antibody Humanization The central feature of this

The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain

A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness

Mutations in this gene are correlated with gastric

This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family

It encodes Disintegrin and metalloproteinase domain-containing protein 10 with similarity to collagens X and VIII and complement factor C1q

Human Hypoxia-inducible Factor 1Α, HIF-1A ELISA Kit , 96T Antibody Humanization The central feature of thisFunctions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis