NOXA1 Polyclonal Antibody, 20ul Modification Enzymes Autoantibodies to the encoded protein

Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis

The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing

and increased activity of this enzyme in infants with hemangiomas causes severe hypothyroidism

These proteins have been implicated in the development of paraneoplastic disorders resulting from an immune response directed against them

It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units

NOXA1 Polyclonal Antibody, 20ul Modification Enzymes Autoantibodies to the encoded proteinThis gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N terminal tetratricopeptide domains and a C terminal Src homology 3 domain. Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains. Multiple transcript variants encoding different isoforms have been found for this gene.