LIMK-2 Polyclonal Antibody, 50ul[BT-AP05020] Centrifuges There is a read-through locus

There is a read-through locus (GeneID: 100526761) that shares sequence identity with this gene and the upstream CCDC169 (GeneID: 728591)

Leukotrienes are important mediators of a number of inflammatory and allergic conditions

This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family

and subsequently forms a complex with IL18 receptor beta subunit

Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3

LIMK-2 Polyclonal Antibody, 50ul[BT-AP05020] Centrifuges There is a read-through locusThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase