OAZ2 Polyclonal Antibody, 20ul Cell Dissociation An important paralog of this

An important paralog of this gene is GSDMD

This protein may also affect cytoskeletal-membrane organization

Mutations in IKBKG result in incontinentia pigmenti

The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding

Negatively regulates TCR (T-cell receptor)

OAZ2 Polyclonal Antibody, 20ul Cell Dissociation An important paralog of thisThe protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. This