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SLP-76(Phospho Tyr128) Polyclonal Antibody, 20ul Immune Cell Analysis This protein has an affinity

SKU: 66529160329

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SLP-76(Phospho Tyr128) Polyclonal Antibody, 20ul Immune Cell Analysis This protein has an affinitySLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic

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Description

This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum

The protein encoded by this gene plays important roles in the determination of centrosome position and segregation

The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity

The expression of this gene can be induced by interleukin 4 in B cells

also known as the tetraspanin family

SLP-76(Phospho Tyr128) Polyclonal Antibody, 20ul Immune Cell Analysis This protein has an affinitySLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic

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