CD63 Polyclonal Antibody, 50ul[BT-AP01593] DNA/RNA Isolation & Purification Down-regulates PDPK1 kinase activity by

Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues

PLK5 (Polo Like Kinase 5) is a Protein Coding gene

Mutations in this gene may be associated with adult-onset sensorimotor neuropathy

Binds DNA on N-box motifs: 5'-CACNAG-3'

This gene may play a role in tumor progression

CD63 Polyclonal Antibody, 50ul[BT-AP01593] DNA/RNA Isolation & Purification Down-regulates PDPK1 kinase activity byCDC42EP3 encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The CDC42 effector protein 3 is involved in actin cytoskeleton re organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in