DYRK2 Polyclonal Antibody, 50ul[BT-AP08668] PCR Series MIM 186880) and a costimulatory

MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells

This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain

Polymorphisms in this gene have been linked to various human diseases| including IgA deficiency| common variable immunodeficiency| and premature ovarian failure

PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules

2004 [PubMed 15175245])

DYRK2 Polyclonal Antibody, 50ul[BT-AP08668] PCR Series MIM 186880) and a costimulatoryDYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1,