TPOR(Phospho-Tyr626) Rabbit Polyclonal Antibody, 50ul Immunology The checkpoint kinase 2 encoded

The checkpoint kinase 2 encoded by CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor

Involved in the RCC1/Ran-GTPase pathway

Alternatively spliced transcript variants encoding the same protein have been found for this gene

Materials: Polystyrene (PS)

The up-regulation of this gene is found to be associated with a number of infectious diseases

TPOR(Phospho-Tyr626) Rabbit Polyclonal Antibody, 50ul Immunology The checkpoint kinase 2 encodedIn 1990 an oncogene v mpl was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue named c mpl was cloned. Sequence data revealed that c mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti sense oligodeoxynucleotides of c mpl inhibited megakaryocyte colony