NFκB-p52 (Cleaved-A454) Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries Mitogen-activated protein kinase (MAPK) signaling

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK)| MAPK kinase (MKK or MEK)| and MAPK kinase kinase (MAPKKK or MEKK)

and it functions as a regulator of lymphocyte differentiation

Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported| with the most common allele| Ile654/Ile655| shown here

The protein is an important drug target for the treatment of type 2 diabetes and stroke

Probable G-protein coupled receptor 34 is a protein that in humans is encoded by the GPR34 gene

NFκB-p52 (Cleaved-A454) Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries Mitogen-activated protein kinase (MAPK) signalingdisease: A chromosomal aberration involving NFKB2 is found in a case of B cell non Hodgkin lymphoma (B NHL). Translocation t(10; 14)(q24; q32) with IGHA1. The resulting oncogene is also called Lyt 10C alpha variant. disease: A chromosomal aberration involving NFKB2 is found in a cutaneous T cell leukemia (C TCL) cell line. This rearrangement produces the p80HT gene which encodes for a truncated 80 kDa protein (p80HT). disease: In B cell leukemia (B