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The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium

The N-terminal half shares moderate homology with regions of calmodulin and M-calpain

Poly [ADP-ribose] polymerase 4 has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase

The protein has 7 transmembrane regions and is located on the cell surface

LZK Polyclonal Antibody, 50ul Sealing Film Trust in the quality andMitogen activated protein kinase kinase kinase 13 encoded by MAP3K13 is a member of serine threonine protein kinase family. Mitogen activated protein kinase kinase kinase 13 contains a dual leucine zipper motif, and has been shown to form dimers oligomers through its leucine zipper motif. Mitogen activated protein kinase kinase kinase 13 can phosphorylate and activate MAPK8 JNK, MAP2K7 MKK7, which suggests a role in the JNK signaling pathway.