DNJC3 Polyclonal Antibody, 20ul Centrifuges These proteins modulate many physiological

These proteins modulate many physiological processes

DCK is clinically important because of its relationship to drug resistance and sensitivity

The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity

Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product

Three transcript variants encoding different isoforms have been found for AKR1C3

DNJC3 Polyclonal Antibody, 20ul Centrifuges These proteins modulate many physiologicalThis gene encodes a protein with multiple tetratricopeptide repeat (TPR) motifs as well as the highly conserved J domain found in DNAJ chaperone family members. It is a member of the tetratricopeptide repeat family of proteins and acts as an inhibitor of the interferon induced, dsRNA activated protein kinase (PKR).