TAD2B Rabbit Polyclonal Antibody, 20ul Pipette Controller The tandem array of 22

The tandem array of 22 large| variable region exons are followed by a constant region| containing 3 exons shared by all genes in the cluster

The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B

though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary

Expression of this gene may be downregulated in pancreatic cancer

|enzyme regulation:Can be activated without removal of the activation peptide

TAD2B Rabbit Polyclonal Antibody, 20ul Pipette Controller The tandem array of 22TADA2B functions as a transcriptional adaptor protein that potentiates transcription through coordination of histone acetyltransferase (HAT) activity and by linking activation factors to basal transcriptional machinery (Barlev et al. 2003