PERK Monoclonal Antibody, 100ul In vitro Assessment May be a transcriptional repressor

May be a transcriptional repressor

A pseudogene located on chromosome 3 has been identified for EZR

The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis

A pseudogene has been identified on chromosome 3q29

It serves a variety of functions

PERK Monoclonal Antibody, 100ul In vitro Assessment May be a transcriptional repressorThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in