TIGD4 Polyclonal Antibody, 100ul Immune Cell Preparation overexpression of this gene during

overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM)

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family| a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane

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Localizes to centrosomes

and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD)

TIGD4 Polyclonal Antibody, 100ul Immune Cell Preparation overexpression of this gene duringThe protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known.