Gab 1(Phospho Tyr627) Polyclonal Antibody, 50ul Cell Screening and Imaging Cyclin dependent kinase 2 associated

Cyclin dependent kinase 2 associated protein 1encoded by CDK2AP1 is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2

and is important for the proliferation and differentiation of T cells

and one GoLoco domain

The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1

Two transcripts

Gab 1(Phospho Tyr627) Polyclonal Antibody, 50ul Cell Screening and Imaging Cyclin dependent kinase 2 associatedThe protein encoded by this gene is a member of the IRS1 like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.