Collagen IV alpha2 (Cleaved-Ser1485) Rabbit Polyclonal Antibody, 20ul Deep Well Plates and regulation of cell proliferation

and regulation of cell proliferation

Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres

a serine/threonine protein kinase catlytic domain in the central region

Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors

For more information on UNC5 proteins

Collagen IV alpha2 (Cleaved-Ser1485) Rabbit Polyclonal Antibody, 20ul Deep Well Plates and regulation of cell proliferationAlpha chains of type IV collagen have a non collagenous domain (NC1) at their C terminus frequent interruptions of the G X Y repeats in the long central triple helical domain (which may cause flexibility in the triple helix) and a short N terminal triple helical 7S domain. Type IV collagen is the major structural component of glomerular basement membranes (GBM) forming a 'chicken wire' meshwork together with laminins proteoglycans and entactin