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APEX2 Rabbit Polyclonal Antibody, 50ul Sampling Tubes HM74 is encoded by two

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APEX2 Rabbit Polyclonal Antibody, 50ul Sampling Tubes HM74 is encoded by twoApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II

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Description

HM74 is encoded by two different genes (GPR109A and GPR109B) that express two distinct proteins

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It is thought to form either a homodimer or heterodimer

The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C

Expression of this gene is associated with a poor prognosis for glioma patients

APEX2 Rabbit Polyclonal Antibody, 50ul Sampling Tubes HM74 is encoded by twoApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II

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