AAT Polyclonal Antibody, 50ul[BT-AP00075] Culture Media The recombination activating gene 1

The recombination activating gene 1 component is thought to contain most of the catalytic activity

Consists of an alpha-helical stretch of 700 AA residues

CLDN6 encodes a component of tight junction strands

was significantly upregulated in human monocytes exposed to interferon alpha

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AAT Polyclonal Antibody, 50ul[BT-AP00075] Culture Media The recombination activating gene 1AASS encodes a bifunctional enzyme (aminoadipate semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway. The N terminal and the C terminal portions of this enzyme contain lysine ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia.