MACC1 Polyclonal Antibody, 100ul Cell Senescence The CD27 antigen cytoplasmic tail

The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein

rapid growth

Inhibits HSPA8/HSC70 ATPase and chaperone activities Diseases associated with HSPH1 include hepatitis d

growth cone guidance

An important paralog of this gene is GK

MACC1 Polyclonal Antibody, 100ul Cell Senescence The CD27 antigen cytoplasmic tailMACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409) HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis free survival (Stein et al. 2009 [PubMed: 19098908]).