UVRAG Polyclonal Antibody, 100ul Antibodies contains seven transmembrane domains
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UVRAG Polyclonal Antibody, 100ul Antibodies contains seven transmembrane domainsThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1 PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left right axis malformation and mutations in this gene have been associated with colon cancer.
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