CCDC8 Polyclonal Antibody, 20ul Vacuum Aspirator The protein encoded by DOK2

The protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

Made of special high-purity polypropylene (PP) polymer can effectively reduce the nonspecific binding of protein/nucleic acid to the tube surface

a calcium-dependent

Multiple polyadenylation sites of this gene have been reported

Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS)

CCDC8 Polyclonal Antibody, 20ul Vacuum Aspirator The protein encoded by DOK2This gene encodes a coiled coil domain containing protein. The encoded protein functions as a cofactor required for p53 mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin like 1. Mutations in this gene are a cause of 3M syndrome 3 (3M3).