Bcl-7a Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding the same protein have been observed for this gene

An important paralog of this gene is GPR137B

and peripheral neuropathy

This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level

It contains a single doublecortin domain and is unable to bind microtubules and to regulate microtubule polymerization

Bcl-7a Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing Several alternatively spliced transcript variantsBCL7A (BCL tumor suppressor 7A) is directly involved, with Myc and IgH, in a three way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high grade B cell non Hodgkin lymphoma. The N terminal segment involved in the translocation includes the region that shares a strong sequence similarity