Phospho-BRCA2 (S3291) Polyclonal Antibody, 20ul Pipette Holder The beta 1 chain has
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Phospho-BRCA2 (S3291) Polyclonal Antibody, 20ul Pipette Holder The beta 1 chain hasInherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is
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