TOP1M Polyclonal Antibody, 20ul Cell Dissociation The heavy chain V region

The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070)| joining (J) genes (see MIM 147010)| and diversity (D) genes (see MIM 146910)

Phosphorylates CTNNB1 at Ser-45

Members of this family are important during development

EIF5A2 is a novel phylogenetically conserved gene for eIF5A and localized in an area of the genome often noted for chromosomal instability in cancers

immediate hypersensitivity

TOP1M Polyclonal Antibody, 20ul Cell Dissociation The heavy chain V regionThis gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.