KMT1B Polyclonal Antibody, 100ul Vacuum Aspirator The encoded protein may also

The encoded protein may also play a role in

Multiple alternatively spliced variants

Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase

a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable

Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC

KMT1B Polyclonal Antibody, 100ul Vacuum Aspirator The encoded protein may alsoHistone lysine N methyltransferase SUV39H2 is a Histone methyltransferase that specifically trimethylates Lys 9 of histone H3 using monomethylated H3 Lys 9 as substrate. H3 Lys 9 trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive